Respiration rate estimation based on independent component analysis of accelerometer data: Pilot single-arm intervention study

Abstract

Background: As the mobile environment has developed recently, there have been studies on continuous respiration monitoring. However, it is not easy for general users to access the sensors typically used to measure respiration. There is also random noise caused by various environmental variables when respiration is measured using noncontact methods in a mobile environment. Objective: In this study, we aimed to estimate the respiration rate using an accelerometer sensor in a smartphone. Methods: First, data were acquired from an accelerometer sensor by a smartphone, which can easily be accessed by the general public. Second, an independent component was extracted to calibrate the three-axis accelerometer. Lastly, the respiration rate was estimated using quefrency selection reflecting the harmonic component because respiration has regular patterns. Results: From April 2018, we enrolled 30 male participants. When the independent component and quefrency selection were used to estimate the respiration rate, the correlation with respiration acquired from a chest belt was 0.7. The statistical results of the Wilcoxon signed-rank test were used to determine whether the differences in the respiration counts acquired from the chest belt and from the accelerometer sensor were significant. The P value of the difference in the respiration counts acquired from the two sensors was.27, which was not significant. This indicates that the number of respiration counts measured using the accelerometer sensor was not different from that measured using the chest belt. The Bland-Altman results indicated that the mean difference was 0.43, with less than one breath per minute, and that the respiration rate was at the 95% limits of agreement. Conclusions: There was no relevant difference in the respiration rate measured using a chest belt and that measured using an accelerometer sensor. The accelerometer sensor approach could solve the problems related to the inconvenience of chest belt attachment and the settings. It could be used to detect sleep apnea through constant respiration rate estimation in an internet-of-things environment.