Purpose: To establish some explicit, feasible, and reproducible predictors for CMS. Materials and methods: This study was a retrospective case study. Data were obtained from 82 patients with medulloblastoma at a single center, Beijing Tiantan Hospital. Based on medical records, we created two independent samples: the CMS group comprising 23 patients and the non-CMS group comprising 23 patients. Pre-operative imaging was studied by performing quantitative assessments of specific indicators. Results: The CMS group showed greater differences in pre-operative imaging data with the non-CMS group. The A axi /d axi ratio in pre-operative MR imaging captured in the axial plane was used to quantify the compression of the cerebellum and brainstem, and significant differences were observed between the CMS group and non-CMS group (p = 0.0002). In the sagittal plane, D sag *d sag was used to quantify the area of the tumor that invaded the brainstem, and significant differences were observed between the two groups (p = 0.0003). In the coronal plane, A cor /d cor was used to quantify the compression of the upper functional brain region, and significant differences were noted between the two groups (p = 0.0219). Additionally, Evans’ index was introduced to quantify the degree of hydrocephalus. The CMS group tended to show an increased Evans’ index (p = 0.0027). Conclusion: Based on pre-operative imaging data, some reproducible predictors, such as A axi /d axi , D sag *d sag , A cor /d cor , and Evans’ index, were established.
CITATION STYLE
Zhang, H., Liao, Z., Hao, X., Han, Z., Li, C., Gong, J., … Tian, Y. (2019). Establishing reproducible predictors of cerebellar mutism syndrome based on pre-operative imaging. Child’s Nervous System, 35(5), 795–800. https://doi.org/10.1007/s00381-019-04075-6
Mendeley helps you to discover research relevant for your work.