Recently, RNAi and microRNAs (miRNAs) have become important tools to investigate the regulatory mechanism of stem cell maintenance and differentiation. In this short review, we give a brief overview of the discovery history, functions, and mechanisms of RNAi and miRNAs. We also discuss the RNAi as a tool to study the stem cell function and the potential future practical applications.
CITATION STYLE
Murashov, A. K. (2017). RNAi and MicroRNA-mediated gene regulation in stem cells. In Methods in Molecular Biology (Vol. 1622, pp. 15–25). Humana Press Inc. https://doi.org/10.1007/978-1-4939-7108-4_2
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