Reflux aspiration and cystic fibrosis

Abstract

Chronic airway infections are the hallmark of cystic fibrosis (CF), an autosomal recessive disease, however it is defined as a multi-organ disease, with characteristic abnormalities in the lung, pancreas and the gastro-intestinal tract. Gastro-oesophageal reflux (GOR) is the retrograde bolus movement into the oesophagus and beyond and can be accompanied by typical symptoms such as heartburn and regurgitation.