A CLINICAL STUDY ON EFFECT OF PUNARNAVADI GHRITA ON MADATYAYA WITH SPECIAL REFERENCE TO WITHDRAWAL SYMPTOMS

Abstract

Madya (alcohol), if taken according to the rules and regulations it produces exhilaration, energy, happiness, nourishment, good health, excellent virility and pleasant intoxication. The disease caused by its abuse is called as Madatyaya (alcoholism). It has clinical symptoms similar to Alcoholism. In the present modern era the youth and middle age generation easily gets attracted towards alcohol to reduce tension and stress ultimately blocking social and economic development and even threaten the health services. Alcoholic patients try to come out of the condition but withdrawal symptoms do not let them to do so. Hence the present study has been done to manage the "Madatyaya" with special reference to withdrawal symptoms in which clinical efficacy of "Punarnavadi Ghritt" was studied on 30 patients of withdrawal symptoms (divided in 3 groups i.e. A, B and C) for 30 days. Hb gm%, TLC, DLC, ESR, LFT were also done to assess the efficacy of the drug. Group-A was treated with the medicine provided by the Drug Deaddiction centre, which was significant (P<0.05) statistically in subjective parameters. Group-B was given the medicine of Drug De-addiction centre and Punarnavadi Ghritta simultaneously, which showed highly significant result (P<0.001) in both subjective and objective parameters. Group-C treated with Punarnavadi Ghritta, showed significant (P<0.05) results in objective parameters. Follow-up was on 15th day and after treatment. Our study revealed that the test drug Punarnavadi Ghritta along with medicine of Drug De-addiction centre is effective in treatment of withdrawal of Madatyaya (alcoholism). Hence it can be taken as a complementary medication for Madatyaya.