Pigmentary dispersion syndrome and glaucoma

Abstract

Pigment dispersion syndrome (PDS) and pigmentary glaucoma (PG) are two successive stages of the same disease process characterized by disruption of the iris pigment epithelium and deposition of the dispersed pigment granules throughout the anterior segment. The classic diagnostic triad that characterizes the pigment dispersion syndrome consists of corneal endothelial pigmentation (Krukenberg spindle, Fig. 38.1); slit-like, radial, mid-peripheral iris transillumination defects (Fig. 38.2); and dense homogeneous pigmentation of the trabecular meshwork (Fig. 38.3). In PDS, the anterior chamber is often deeper than normal both centrally and peripherally. © 2010 Springer-Verlag New York.