Ventromedial and orbital prefrontal neurons differentially encode internally and externally driven motivational values in monkeys

161Citations
Citations of this article
322Readers
Mendeley users who have this article in their library.

Abstract

The value of events that predict future rewards, thereby driving behavior, is sensitive to information arising from external (environmental) and internal factors. The ventral prefrontal cortex, an anatomically heterogeneous area, has information related to this value. We designed experiments to compare the contribution of two distinct subregions, orbital and ventromedial, of the ventral prefrontal cortex to the encoding of internal and external factors controlling the perceived motivational value. We recorded the activity of single neurons in both regions in monkeys while manipulating internal and external factors that should affect the perceived value of task events. Neurons in both regions encoded the value of task events, with orbitofrontal neurons being more sensitive to external factors such as visual cues and ventromedial neurons being more sensitive to internal factors such as satiety. Thus, the orbitofrontal cortex emphasizes signals for evaluating environment-centered, externally driven motivational processes, whereas ventromedial prefrontal cortex emphasizes signals more suited for subject-centered, internally driven motivational processes. Copyright © 2010 the authors.

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Cite

CITATION STYLE

APA

Bouret, S., & Richmond, B. J. (2010). Ventromedial and orbital prefrontal neurons differentially encode internally and externally driven motivational values in monkeys. Journal of Neuroscience, 30(25), 8591–8601. https://doi.org/10.1523/JNEUROSCI.0049-10.2010

Readers over time

‘10‘11‘12‘13‘14‘15‘16‘17‘18‘19‘20‘21‘22‘23‘24‘25015304560

Readers' Seniority

Tooltip

PhD / Post grad / Masters / Doc 149

59%

Researcher 70

28%

Professor / Associate Prof. 28

11%

Lecturer / Post doc 6

2%

Readers' Discipline

Tooltip

Psychology 85

35%

Neuroscience 75

31%

Agricultural and Biological Sciences 61

25%

Medicine and Dentistry 21

9%

Save time finding and organizing research with Mendeley

Sign up for free
0