A quarter century of granzymes

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Abstract

Granzymes (Grs) were discovered just over a quarter century ago. They are produced by cytotoxic T cells and natural killer cells and are released upon interaction with target cells. Intensive biochemical, genetic, and biological studies have been performed in order to study their roles in immunity and inflammation. This review summarizes research on the family of Grs. © 2012 Macmillan Publishers Limited All rights reserved.

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Ewen, C. L., Kane, K. P., & Bleackley, R. C. (2012, January). A quarter century of granzymes. Cell Death and Differentiation. https://doi.org/10.1038/cdd.2011.153

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