Traditional ex vivo expansion of adult stem cells yields an insufficient quantity of less potent cells. Here we describe the fabrication of decellularized matrix deposited by synovium-derived stem cells (SDSCs). This matrix could serve as a three-dimensional expansion system to rejuvenate cells for proliferation and tissue-specific differentiation potential, which could benefit cartilage regeneration. The decellularized stem cell matrix (DSCM) might be a powerful system for tissue engineering and regeneration.
CITATION STYLE
Li, J., & Pei, M. (2018). A protocol to prepare decellularized stem cell matrix for rejuvenation of cell expansion and cartilage regeneration. In Methods in Molecular Biology (Vol. 1577, pp. 147–154). Humana Press Inc. https://doi.org/10.1007/7651_2017_27
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