Optically pumped magnetoencephalography in epilepsy

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Abstract

We demonstrate the first use of Optically Pumped Magnetoencephalography (OP-MEG) in an epilepsy patient with unrestricted head movement. Current clinical MEG uses a traditional SQUID system, where sensors are cryogenically cooled and housed in a helmet in which the patient’s head is fixed. Here, we use a different type of sensor (OPM), which operates at room temperature and can be placed directly on the patient’s scalp, permitting free head movement. We performed OP-MEG recording in a patient with refractory focal epilepsy. OP-MEG-identified analogous interictal activity to scalp EEG, and source localized this activity to an appropriate brain region.

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Vivekananda, U., Mellor, S., Tierney, T. M., Holmes, N., Boto, E., Leggett, J., … Walker, M. C. (2020). Optically pumped magnetoencephalography in epilepsy. Annals of Clinical and Translational Neurology, 7(3), 397–401. https://doi.org/10.1002/acn3.50995

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