Laboratory diagnosis of Crimean-Congo hemorrhagic fever

Abstract

Crimean-Congo hemorrhagic fever virus (CCHFV) can induce in humans a severe multisystem syndrome associated with fever, shock, and hemorrhages. In absence of specific clinical symptoms, physicians need a rapid and reliable diagnosis to reinforce the measures of safety (barrier nursing), and possibly to initiate quickly a suitable antiviral treatment. Equally, a differential diagnosis with other agents responsible of hemorrhagic fevers according to epidemiological features has to be undertaken [18, 51].