Applications of biochips fabricated by femtosecond lasers

Abstract

The ability of femtosecond laser processing to simultaneously fabricate three-dimensional microfluidic, micro-optical, microelectronic, and micromechanic components inside glass microchips provides great advantages over conventional fabrication techniques for fabricating various biochips. This chapter introduces applications of biochips fabricated by femtosecond laser processing to biosensing based on surface-enhanced Raman scattering spectroscopy, efficient mixing of fluids, single cell detection, manipulation and sorting of cells, concentration analysis of liquid samples, and detection and elucidation of the functions of microorganisms and bacteria.