Behavioral changes of patients after orthognathic surgery develop on the basis of the loss of vomeronasal organ: A hypothesis

Abstract

We introduce a hypothesis which presumes that damage to the vomeronasal organ during a Le Fort I osteotomy of the maxilla for the purpose of orthognathic surgical treatment of congenital or acquired jaw deformities affects the patient's social life in terms of the selection of mates and establishment of relationships. The vomeronasal organ is chemosensory for pheromones, and thus registers unconscious olfactory information which might subsequently act on the limbic system of an individual and influence the selection of mates. We believe it is connected to an inhibitory feedback mechanism which is responsible for the exclusion of inappropriate mates. When the vomeronasal organ is removed or damaged during a maxillary osteotomy, the inhibitory function is lost, the patient loses the involuntary ability to exclude inappropriate mates, may become less committed to an existing mate, or even become promiscuous.