FORMULATION AND EVALUATION OF SUN PROTECTIVE TOPICAL PREPARATION

Abstract

In recent days, many people are facing problem of sun tanning and darkening of skin. Sun tanning causes erythema (sunburn inflammation), reddening of skin, local or systemic immunosuppression, photoaging and photocarcinogenesis. Skin is a delicate organ of body, thus by considering the facts related to this attempt are made to develop cream having Sunprotective as well as Fairness activity with improved user compliance and avoidance of undesirable effect. It is reported that Oxybenzone gives protection against UV B rays. Hence the present work is a humble attempt to evaluate sunscreen activity of oxybenzone along with the fairness activity of Arbutin. The procured sample of the chemical material was first evaluated for their quality by determining colour, odour, pH, melting point, residue on ignition, loss on drying and % purity. Proper cream base was formulated by taking different trials. Three different base trials were then evaluated. On the basis of evaluation results of pH, viscosity and appearance the base trial 2 (B2) was selected for incorporation of active ingredients into the base. Cream containing 6 % of Oxybenzone and 1.5 % of Arbutin was selected for the evaluation of fairness activity and from the observation, it was concluded that the cream improves complexion, makes the skin soft and ensure ease of application. Hence it is concluded that it may be used as Sunscreen and Fairness cream.