Security measures of a master regulator

  • Alessi D
  • Kulathu Y
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Abstract

At last, the crystal structure is revealed for the catalytically active mTOR kinase enzyme, a master regulator of cell growth. The structure indicates a gatekeeper mechanism that controls substrate access to the active site.

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Alessi, D. R., & Kulathu, Y. (2013). Security measures of a master regulator. Nature, 497(7448), 193–194. https://doi.org/10.1038/nature12101

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