Goodpasture disease (GD) is a rare autoimmune disorder characterized by the development of pathologic autoantibodies against both glomerular and alveolar basal membranes. Approximately one third of the patients with GD are also positive for anti-neutrophil cytoplasmic antibody (ANCA). In this case report, a 74-year-old woman was diagnosed as having myeloperoxidase (MPO)-ANCA-positive GD with severe aortic valve stenosis (AS). She underwent immunosuppressive therapy and plasmapheresis that led to GD remission. Whether a cardiac surgery affects a MPO-ANCA-positive GD in remission is unknown. We reported the outcomes after aortic valve replacement for severe AS in a patient with MPO-ANCA-positive GD.
CITATION STYLE
Kataoka, G., Asano, R., Sato, A., Tatsuishi, W., & Nakano, K. (2016). Aortic valve replacement in a patient with MPO-ANCA-positive Goodpasture disease. Surgical Case Reports, 2(1). https://doi.org/10.1186/s40792-016-0230-x
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