The Value of Intraoperative Parathyroid Hormone Monitoring in Primary Hyperparathyroidism Cases That Are Localized with Two Imaging Studies

Abstract

Minimally invasive parathyroidectomy has become a preferred approach for primary hyperparathyroidism in patients with a single parathyroid adenoma. Preoperative localization studies and intraoperative parathyroid hormone (ioPTH) are important adjuncts, with surgeons often relying on ioPTH to confirm cure. The utility of ioPTH in patients with two concordant preoperative localization studies that accurately predict single parathyroid adenomas, remains controversial. This chapter explores the evidence for the use of ioPTH is this setting.