The use of combined pharmacotherapy and hyperbaric oxygen in the treatment of sudden sensorineural hearing loss

Abstract

Aim: Sudden sensorineural hearing loss (SSNHL) involves acute unexplained hearing loss, nearly always one-sided of 30dB or greater over at least three contiguous audiometric frequencies. The aetiology of SSNHL is mostly unknown. According to the literature, the causes include vascular, microbial and autoimmune problems. There is still no agreed standard treatment. The aim of the paper was to evaluate the results of combined pharmacotherapy and hyperbaric oxygen therapy in patients with idiopathic sudden deafness. Material/Methods: The study was carried out on 40 patients with SSNHL. The patients were divided into two groups: Group I - 24 patients treated with the combined pharmacotherapy and hyperbaric oxygen therapy and group II - 16 patients treated only pharmacologically. The patients from Group 1 were treated in the Centre of Hyperbaric Therapy CREATOR Ltd. in Lodz, Poland. Each patient underwent 15 sessions in a hyperbaric chamber. In all patients, the percentage of hearing loss for the selected frequencies was assessed before and after the therapy according to Sabine and Fowler. Results: The group of 40 patie nts aged from 33 to 77 years (mean 52.4) included 21 females and 19 males. Group I consisted of 24 patients, 11 females and 13 males, group II consisted of 16 patients, 10 females, and 6 males. After therapy, the mean hearing level in all patients improved by 27.14%, in Group I - by 34.34%, in Group II - by 16.3%. Conclusions: Early hyperbaric oxygen therapy combined with steroid therapy improves prognosis and shows good results in sudden hearing loss treatment.