A collaborative effort will facilitate the collection of adequate and well-controlled pediatric efficacy and safety clinical trial data to inform pediatric use of new drugs to treat T2D. An approach relying on a multiarm trial is one particularly attractive approach that leverages efficiencies gained from use of a shared control group, with efficiencies gained from a shared research infrastructure. Success in pediatric drug development has often involved collaboration. Indeed, reliance on consortia-based approaches to evaluate novel therapies was successful for other relatively uncommon pediatric diseases (e.g., juvenile idiopathic arthritis and schizophrenia) and should be met with similar success in T2D.
CITATION STYLE
Karres, J., Pratt, V., Guettier, J. M., Temeck, J., Tamborlane, W. V., Dunger, D., … Tomasi, P. (2014, October 1). Joining forces: A call for greater collaboration to study new medicines in children and adolescents with type 2 diabetes. Diabetes Care. American Diabetes Association Inc. https://doi.org/10.2337/dc14-0494
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