Metal Organic Framework-Molecularly Imprinted Polymer as Adsorbent in Matrix Solid Phase Dispersion for Pyrethroids Residue Extraction from Wheat

Abstract

Metal organic frameworks-molecular imprinting polymers (MOFs-MIPs) were applied as dispersants of matrix solid phase dispersion (MSPD) followed by gas chromatography-tandem mass spectrometry (GC-MS/MS) to selectively analyze pyrethroids in wheat. MOFs-MIPs characterized by a series of instrumental techniques and the adsorption properties researched by isothermal, kinetics, thermodynamics, and selective binding experiments. The results revealed that the MOFs-MIPs had a larger adsorption capacity (474.56 mg g−1) and fast adsorption time (20 min). What is more, MOFs-MIPs-MSPD procedure clearly increased extraction efficiency and decreased the consumption of organic solvent. The better recoveries of pyrethroids were reached by optimizing MSPD conditions. Under the excellent conditions, the linearity ranges of pyrethroids in wheat samples were obtained varying from 10 to 1000 ng g−1; the limits of detection were in the range of 1.8–2.8 ng g−1 and the precisions were lower than 6.3%. At the same time, the method was successfully applied for detection of three pyrethroids residue in six kinds of wheat samples and cyhalothrin residue detected in one wheat was 23.96 ng g−1, which is lower than the maximum residue limits allowed by the Ministry of Agriculture of the People’s Republic of China. The developed MOFs-MIPs-MSPD-GC-MS/MS method displayed high selectivity, absorbability, simplicity, rapidity, sensitivity, and excellent practical food control applicability.