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Background: Immunocompromised patients, such as systemic lupus erythematosus (SLE) sufferers have an increased risk of mortality, following influenza infection. In the recent pandemic, influenza A H1NI virus caused 18449 deaths, mainly because of adult respiratory distress syndrome or bacterial co-infections.Case Presentation: In this case report, an SLE patient with viral-induced septic shock, without overt pulmonary involvement, is discussed. The patient was administered oseltamivir and supportive treatment, including wide-spectrum antibiotics, vasopressors and steroids, according to the guidelines proposed for bacterial sepsis and septic shock. She finally survived and experienced a lupus flare soon after intensive care unit (ICU) discharge.Conclusions: To our knowledge, this is the first case to report severe septic shock from influenza A/H1N1 virus, without overt pulmonary involvement. © 2011 Tselios et al; licensee BioMed Central Ltd.
Tselios, K., Tsioka, R., Sarantopoulos, A., Mouloudi, E., & Boura, P. (2011). Influenza A/H1N1 septic shock in a patient with systemic lupus erythematosus. A case report. BMC Infectious Diseases, 11. https://doi.org/10.1186/1471-2334-11-358