History, Advancements, and Future Strategies

Abstract

Since the recognition of the genetic predisposition to breast and ovarian cancers, researchers have verified their genetic involvement and causative genes. Furthermore, treatment strategies and prevention care options to reduce the overall risk for hereditary cancers have been established based on rapid advancements in gene sequencing. Owing to the great efforts of our predecessors, the quality of life of patients diagnosed with hereditary tumors has been improved. This chapter introduces the history, advancements, and future strategies on hereditary breast and ovarian cancer (HBOC), which has a high prevalence of breast and ovarian cancer. In any field of medicine, first, clinical questions that foresee the truth arise; researchers then seek the truth, and clinicians deploy their knowledge in the medical field.