Comparison of the efficacy of dextrose prolotherapy and ozone in patients with knee osteoarthritis: A randomized cross-sectional study

2Citations
Citations of this article
18Readers
Mendeley users who have this article in their library.

Abstract

This study aimed to compare the effectiveness of dextrose prolotherapy, ozone therapy, and home exercise programs in patients with knee osteoarthritis. Seventy-five patients with knee osteoarthritis were divided into three groups, with 25 in each group. At week 0 (baseline), week 3, and week 6, 12.5% dextrose (intraarticular and periarticular) was administered to the dextrose prolotherapy group. At week 0 (baseline), week 1, and week 2 15 µg/mL ozone (intraarticular and periarticular) was administered to the ozone therapy group. Both groups were also given a home exercise program. The third group was given a home-based exercise therapy program for 12 weeks. All groups were evaluated for VAS, WOMAC, TUG, ROM-active, and ROM-passive values at weeks 0 (baseline), 6, and 12. Ozone therapy more effectively improved VAS scores than dextrose prolotherapy and VAS and WOMAC scores than home-based exercise therapy in the 6th week. Ozone therapy also more effectively improved VAS and WOMAC-stiffness scores than dextrose prolotherapy and VAS, WOMAC, and ROM-active scores than home-based exercise therapy in the 12th week. Both dextrose prolotherapy and ozone therapy are effective in knee osteoarthritis treatment. Ozone therapy should be used in suitable cases rather than dextrose prolotherapy.

Cite

CITATION STYLE

APA

Baygutalp, F., Çelik, M., Öztürk, M. U., Yayık, A. M., & Ahıskalıoğlu, A. (2021). Comparison of the efficacy of dextrose prolotherapy and ozone in patients with knee osteoarthritis: A randomized cross-sectional study. Applied Sciences (Switzerland), 11(21). https://doi.org/10.3390/app11219991

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free