Simultaneous Systematic Approach to Enable Predictive, Preventive and Personalized Medicine – Women Healthcare as a Case Study

Abstract

A simultaneous systematic analysis approach is presented to enable a responsible, affordable Predicitve, Preventive, Personalized and Participatory Medicine (PPPPM) to ALL citizens. It is our contention that time has come and science and technology have reached the stage to relate to the individual functioning in the physical and mental surroundings, as one complex system. The targeted platform is envisioned to provide the broadest possible insights through an open, innovative systematic effort focusing on a specific phenomenon or disease. It will enable sharing concurrently all findings and combining all acquired knowledge, technologies and expertise. The leading professionals from various research disciplines (including life sciences, medicine, engineering, informatics, humanities, social sciences, environmental studies, etc.), will be integrated, utilizing our CHEST methodology (Converging Humanities, Education, Science and Technology) to share knowledge and tools while overcoming conceptual, lingual and other gaps. Furthermore, involving ethics professionals, for example, at the basic science level together with other experts from academia, government, regulatory agencies, industries and patients groups, bridging the different concepts and interests, will ensure the wellbeing and profitable outcome to ALL. To further present our approach, drug studies are suggested, focusing on four major disease classes: cancer, neurodegenerative diseases, metabolic disorders and infectious diseases. The matrix multi-layer approach will be applied comparing healthy individuals, diagnosed but not treated and treated patients. This review article focuses on women healthcare as a powerful imprinting group from conception throughout the individual’s life-span. Moreover, women were and are the driving force in applying healthcare at the personal, family and community levels. The envisioned possible outcome will provide a comprehensive insight on the individual functioning over time and place, enabling responsible, equal and personalized healthcare to ALL, yielding major economic and sociological impact and heralding new era of wellbeing to the global society.