The use of in vitro methods of infecting cell lines to test new treatments for SARS-CoV-2 does not always recapitulate the real context of the infection, and mouse models for SARS-CoV-2 infection are limited. Here we describe a novel ex vivo approach by collecting, isolating, and culturing nasal epithelial cells obtained from patients with COVID-19. This technique allows us to study immune responses and test new treatments directly on cells from patients naturally infected with SARS-CoV-2.
CITATION STYLE
Antunes, K. H., & de Souza, A. P. D. (2022). Isolation and Cell Culture of Human Nasopharyngeal Cells: A Model for Testing Immune Response and Antiviral Treatment. In Methods in Molecular Biology (Vol. 2511, pp. 367–373). Humana Press Inc. https://doi.org/10.1007/978-1-0716-2395-4_28
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