Effectiveness of diaphragmatic stimulation with single-channel electrodes in rabbits

  • Ghedini R
  • Espinel J
  • Felix E
  • et al.
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Abstract

Every year, a large number of individuals become dependent on mechanical ventilation because of a loss of diaphragm function. The most common causes are cervical spinal trauma and neuromuscular diseases. We have developed an experimental model to evaluate the performance of electrical stimulation of the diaphragm in rabbits using single-channel electrodes implanted directly into the muscle. Various current intensities (10, 16, 20, and 26 mA) produced tidal volumes above the baseline value, showing that this model is effective for the study of diaphragm performance at different levels of electrical stimulationA cada ano um grande número de pessoas perde a função do diafragma tornando-se dependentes de ventilação mecânica. As principais causas são o trauma raquimedular da região cervical e as doenças neuromusculares. Desenvolvemos um modelo experimental para avaliar o desempenho da estimulação elétrica do diafragma em coelhos com eletrodos monocanais implantados diretamente neste músculo. Foram aplicadas diferentes intensidades de correntes (10, 16, 20 e 26 mA), as quais geraram volumes correntes acima dos valores basais, mostrando que este modelo é eficaz para estudar o desempenho do diafragma sob diferentes tipos de estimulação elétrica

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APA

Ghedini, R. G., Espinel, J. de O., Felix, E. A., Paludo, A. de O., Mariano, R., Holand, A. R. R., & Andrade, C. F. (2013). Effectiveness of diaphragmatic stimulation with single-channel electrodes in rabbits. Jornal Brasileiro de Pneumologia, 39(4), 490–494. https://doi.org/10.1590/s1806-37132013000400014

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