Organic Syntheses Based on Name Reactions and Unnamed Reactions

Abstract

This chapter discusses several organic syntheses based on name reactions. The chapter discusses the Abramov phosphonylation of aldehydes by means of phosphorodiamidates. The Adler phenol oxidation is reviewed. Oxidation of o-alkoxyphenols with sodium metaperiodate is presented to afford 6,6-spiro-2,4-cyclohexadienones, which dimerize spontaneously to a Diels–Alder adduct. In the Alder (Ene) reaction, thermal or catalytic sigmatropic rearrangement is reviewed with H-transfer and C–C bond formation with chiral induction. Synthesis of polysubstituted benzenes by a Diels–Alder reaction of cyclohexadienes with acetylenes, via bicyclooctadienes, is presented. The Allen–Millar–Trippett phosphonium rearrangement is discussed. Carbonylation of cyclic amines, hydroformylation (CO–H2) of amino olefins catalyzed by metal (Pd, Ru, Rh) complexes are also reviewed in the chapter. Synthesis of hydroxamic acids from aldehydes and N-sulfonylhydroxylamine is reviewed. It is also used as a color test for aldehydes.