Preparation of Heptakis(6-0-(/?-tosyl))-/j-cyclodextrin And Heptakis(6-o-(/>-tosyl))-2-0-(/?-tosyl)-/j-cyclodextrin And Their Conversion To Heptakis(3,6-anhydro)-/j-cyclodextrin

Abstract

Heptakis(6-0-(/>-tosyl))-/?-cyclodextrin and heptakis(6-0-(/Mosyl))-2-O-(/>-tosyl)-/J-cyclodextrin were prepared by the reaction of /?-cyclodextrin with p-tosyl chloride in pyridine. They were converted to heptakis(3,6-anhydro)-/?-cyclodextrin, constituted from alternative (1C4) glucose units. © 1991, The Pharmaceutical Society of Japan. All rights reserved.