Recent developments in the molecular biology of pituitary tumors

Abstract

Significant advances have been made in the analysis of molecular mechanisms leading to pituitary tumor development in recent years. Studies of familial pituitary tumors, oncogenes and tumor suppressor genes have all contributed to this knowledge. Cytogenetic studies, PCR, RT-PCR and in situ hybridization have also had significant contributions in this field. Recent studies of microRNAs and DNA microarray analyses continue to provide new insights into the pathogenesis of pituitary tumors. © 2010 Springer-Verlag New York.