Identification of malignant tumors in the liver

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Abstract

To date, surgery is the only curative treatment option for patients with resectable metastases in the liver and is regarded as standard-of-care. However, recurrence rates remain high, which might partly be explained by the inability of conventional technologies to detect small lesions. Near-infrared fluorescence imaging is able to detect lesions as small as 1 mm, but only if they are localized on or several millimeters below the liver surface. Several studies reported the identification of otherwise undetectable liver tumors using near-infrared fluorescence imaging. Research in the coming years will have to determine if this technology is truly beneficial for patients requiring resection of malignant liver tumors.

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Handgraaf, H. J. M., Verbeek, F. P. R., Van de Velde, C. J. H., Hutteman, M., & Vahrmeijer, A. L. (2015). Identification of malignant tumors in the liver. In Fluorescence Imaging for Surgeons: Concepts and Applications (pp. 159–168). Springer International Publishing. https://doi.org/10.1007/978-3-319-15678-1_16

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