P652The effects of two exercise therapy methods on cardio-metabolic risk factors in diabetic overweight middle-aged females

Abstract

Background/Introduction: The beneficial effects of exercise on glucose control in individuals with type 2 diabetes have been shown to be associated with reduction of several cardiometabolic risk factors.Therefore, the purpose of this study was to investigate the effects of two different exercise training on cardiometabolic risk factors in diabetic overweight middle‐aged females. Methods: Fifty two overweight and diabetic females (age; 45‐60 years old and fasting blood glucose ≥126 mg/dL) were recruited to participate in this study. Participants were randomly assigned into sprint interval training (SIT) group (n=17), concurrent resistance‐endurance training (CRET) group (n=17) and control group (n=18). The combined strength‐endurance group completed 12 weeks, three sessions per week of endurance training at 60% of maximal heart rate and two sessions of resistance training at 70% 1‐RM. Intense interval training group completed three sessions/week of four to ten repetitions during 30 seconds. Wingate on ergometer included 10 weeks of concurrent resistance‐endurance training and intense interval training. Fasting glucose, insulin, insulin resistance, high sensitivity C‐reactive protein (hs‐CRP), interleukin‐6 (IL‐6), systolic blood pressure, diastolic blood pressure, body fat, waist circumference (WC), waist to hip ratio (WHR) and body mass index (BMI) were measured before and after the both training interventions. Results: There was a significant change in hs‐CRP (P=0.001) in SIT group (2.3±0.56), while there was only a trend observed in CRET (2.36±1.45) (P=0.062). Significant differences were also observed in insulin resistance index (HOMA‐IR) in SIT group (P=0.000) and CRET group (P=0.008) compared to control group; however, no significant difference was found between the experimental conditions in fasting blood glucose concentrations (P=0.171). Conclusions: SIT appears to have more beneficial effects on cardiometabolic risk factors compared with CRET represented with a greater reduction in hs‐CRP levels. (Table Presented).