Effect of sarang banua (clerodendrumfragransvent willd) leaves extract on serum globulin levels of rabbit (oryctolagus cuniculus)

Abstract

Sarang banua plants are found in Simalungun, North Sumatra, Indonesia, which have been used by the community as traditional medicinal plants and is a type of ClerodendrumfragransVent Willd, including the family Verbanaceae. The study design was completely randomized design (CRD) with five treatments namely 1% Na-CMC (K1, negative control), bovine serum antigen (K2), ethanol extract of sarang banua leaf 200 mg/kg BW (K3), ethanol extract of sarang banua leaf 200 mg/kg BW with bovine serum antigen (K4) and ethanol extract of sarang banua leaf 150 mg/kg BW with bovine serum antigen (K5). The results showed that administration of ethanol extract of sarang banua leaf (ClerodendrumfragransVent Willd) significantly affected serum globulin levels of rabbits (Oryctolagus cuniculus). The ethanol extract of sarang banua leaves 200 mg/kg BW with bovine serum antigen (K4) produced the highest serum globulin levels of rabbits (12.91 mg/mL).