Cubosomes Nanoparticles: Recent Advancements in Drug Delivery

  • Suresh A
  • Kallingal A
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Abstract

Cubosomes are nanoparticles that are square or rounded and have internal cubic lattices. Cubosomes are a one-of-a-kind creation that combines food science, differential geometry, biological membranes, and digestion into a single entity. Because of its discovery and nomination, self-assembled cubosomes have developed in appeal as excellent drug delivery methods. Cubosomes are thermodynamically stable and contain a honeycomb-like structure of bicontinuous water and lipid domains. It is produced into bilayers inside the surfactant and wrapped into a three-dimensional, intermittent, and minimum surface, resulting in a densely packed structure. The material is a bicontinuous cubic liquid crystalline form that is optically clear and very viscous, with a unique composition in the nanometer range. Overall, cubosomes are critical in nano drug preparations for melanoma treatment because to their intrinsic benefits, which include higher surface area and cuboidal structures, which allow for larger drug payloads. They’re easy to make, and their biodegradability allows them to encapsulate hydrophobic, hydrophilic, and amphiphilic chemicals while releasing bioactive substances in a regulated manner. Dispersion of biocompatible and bioadhesive cubosomes Cubosomes are tiny structures that may be administered in a variety of methods, including oral, percutaneous, and parenteral, due to their features. Cubosomes have a wide range of uses and are represented by a number of characteristics. As a result, cubosomes are gaining in popularity in the pharmaceutical testing industry.

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Suresh, A. M., & Kallingal, A. (2020). Cubosomes Nanoparticles: Recent Advancements in Drug Delivery. International Journal of Medical & Pharmaceutical Sciences, 10(02). https://doi.org/10.31782/ijmps.2020.10201

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