Structural, physicochemical characterization and antimicrobial activities of a new Tetraaqua bismaleato Iron(II) complex

Abstract

Tetraaqua bismaleato iron(II) [Fe(C4H3O4)2(H2O)4], (1) is a new synthetic antimicrobial agent. Thermal analysis shows that the dehydration of the compound occurs in agreement with the structure. The single crystal salt crystallizes in the triclinic space group P-1 with a = 5.171(2) Å, b = 7.309(3) Å, c = 9.731(3) Å, α = 109.15(2)°, β = 115.02(2)°, γ = 92.42(1)°, V = 313.6(3) Å3 and Z = 1. Three dimensional network is formed by strong intermolecular O - H ...O hydrogen bonds. Magnetic susceptibility measurements of 1 in the range 2-300 K exhibited paramagnetic behavior at high temperature. However, at low temperature, the susceptibility data showed weak antiferromagnetic interactions between the local spins. Antimicrobial activity of 1 was tested. It showed high response against gram-positive and gram-negative bacteria as well as fungi and the MIC and IC50 values ranged from 8 to 256 μg.mL-1 and from 1.38 to 22.19 μg.mL-1, respectively.