Active efflux of antimicrobial agents in wild-type strains of Enterococci

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Abstract

Enterococci are intrinsically resistant to numerous antimicrobial agents. We examined the energy-dependent efflux of radiolabeled drugs from four reference strains of Enterococcus faecalis and a strain of Enterococcus faecium and found that most strains pumped out norfloxacin and chloramphenicol. Efflux of tetracycline was detected only in certain strains.

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Lynch, C., Courvalin, P., & Nikaido, H. (1997). Active efflux of antimicrobial agents in wild-type strains of Enterococci. Antimicrobial Agents and Chemotherapy, 41(4), 869–871. https://doi.org/10.1128/aac.41.4.869

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