Abstract
An enzyme-linked immunosorbent assay (ELISA) based on the recombinant Toscana virus nucleoprotein (rN) has been developed. Its sensitivity and specificity for the detection of virus-specific immunoglobulins G and M in human sera were similar to those of the ELISA that is based on an antigen extracted from infected mouse brain and that is routinely used for serodiagnosis.
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CITATION STYLE
Ciufolini, M. G., Fiorentini, C., Di Bonito, P., Mochi, S., & Giorgi, C. (1999). Detection of Toscana virus-specific immunoglobulins G and M by an enzyme-linked immunosorbent assay based on recombinant viral nucleoprotein. Journal of Clinical Microbiology, 37(6), 2010–2012. https://doi.org/10.1128/jcm.37.6.2010-2012.1999
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