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Acetylcholine addition and electrical stimulation of dissociated neurons from an extended subthalamic area – A pilot study in the rat

IFMBE Proceedings (2007) 16(1) 521-524
DOI: 10.1007/978-3-540-73044-6_133
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Abstract

Addition of acetylcholine to cultures of STN area’s (5 steps of 10 μM with a step interval of 1000 s) show a direct and longlasting reduction of STN activity. Low frequency stimulation (20 Hz, 500 block pulses) increases STN activity, while high frequency stimulation (80 Hz, 2000 block pulses) reduces STN activity, even after the stimulation period of 25 seconds.

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Heida, T., Usunoff, K. G., & Marani, E. (2007). Acetylcholine addition and electrical stimulation of dissociated neurons from an extended subthalamic area – A pilot study in the rat. In IFMBE Proceedings (Vol. 16, pp. 521–524). Springer Verlag. https://doi.org/10.1007/978-3-540-73044-6_133

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