Effect of Black Tea (camellia sinensis) on Serum Adiponectin Level in Atherogenic Diet Rats

Abstract

The aim of this study is to investigate the effect of black tea administration on serum adiponectin level in male Wistar fed with atherogenic diet (AD). This study was designed as a true experimental design that assigns 20 rats, and divides them into four groups as follows: P1 (AD 3 months); P2, P3, and P4 (3 months AD + black tea extract administration at dosage 0.015gr/day, 0.03gr/day, 0.045gr/day, respectively). Serum adiponectin level was measured using ELISA method. This study demonstrated that there is an elevation trend of adiponectin level as the dose elevated. However, serum adiponectin level in AD-only group (380.6ng/mL) was not significantly different with treatment group (386.93ng/mL, 404.27ng/mL, and 416.6ng/mL in P2, P3, and P4, respectively) (ANOVA, p = 0.352). Furthermore, there was no significant association between the dosage of black tea and adiponectin levels (Pearson correlation test, p = 0.073, r = 0.373). We concluded that black tea extract increased serum adiponectin level insignificantly in atherogenic diet rats.