Pharmacological Applications of Biocompatible Carbon Nanotubes and Their Emerging Toxicology Issues

Abstract

Since their discovery in 1991, carbon nanotubes (CNTs) have been studied for their application as diagnostic tools, chemical sensors, and vectors for drug delivery. Carbon nanotubes are of great interest because of their unique array of physical and chemical properties, including their high aspect ratio, ultralight weight, high mechanical strength, high electrical conductivity, high thermal conductivity, and high surface area. The unique properties of carbon nanotubes also raise substantial concern about their potentially toxic effects on the environment and human health. This review focuses on the current pharmacological applications and emerging toxicology issues of biocompatible carbon nanotubes. Carbon nanotubes as agents for drug delivery, cancer therapeutics, along with their in vivo challenges and potential toxicity are discussed.