Temporal relationships among depression, medical comorbidity, and death or cardiovascular disease (CVD) events are complex. Clarifying temporal relationships may enhance current insight regarding the nature of the association of depression with poor outcomes. The temporal relation of depression symptoms (DS; score
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Boulware, L. E., Liu, Y., Fink, N. E., Coresh, J., Ford, D. E., Klag, M. J., & Powe, N. R. (2006). Temporal relation among depression symptoms, cardiovascular disease events, and mortality in end-stage renal disease: contribution of reverse causality. Clinical Journal of the American Society of Nephrology : CJASN, 1(3), 496–504. https://doi.org/10.2215/CJN.00030505
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