Synthesis of propargylamines catalyzed by nano-colloidal silica-tethered polyhedral oligomeric silsesquioxanes with eight branches of 3-aminopropyltriethoxysilane as an efficient catalyst

Abstract

Here, we report a family of polyhedral oligomeric silsesquioxanes with eight branches of 3-aminopropyltriethoxysilane tethered to nano-colloidal silica, which is characterized by 1H nuclear magnetic resonance spectroscopy, elemental analysis (CHN analysis), dynamic light scattering, scanning electron microscopy, energy-dispersive spectroscopy and thermogravimetric analysis. Furthermore, a clean, efficient, straightforward one-pot multicomponent synthetic method for the synthesis of propargylamines in good yields has been devised using nano-colloidal silica-tethered polyhedral oligomeric silsesquioxanes with eight branches of 3-aminopropyltriethoxysilane as superior catalyst under microwave irradiation.