Nanoceria and Its Biomedical Relevance

Abstract

Nanoceria is a nanosized particle preparation of cerium oxide. It shows mixture of cerium in the 3+ and 4+ states on the nanoparticle surface, giving it interesting redox properties. Nanoceria shows effective biological antioxidant properties, which makes it a great candidate for biomedical applications. Many studies have shown promising results on therapeutic potential of nanoceria in diseases like cancer, diabetes, atherosclerosis, and neurodegenerative diseases. Meanwhile, other studies explored biodistribution and toxicity of nanoceria. This review article describes nanoceria, its relevant biomedical applications, and adverse effects, based on previously reported studies.