Abnormal cardiovascular reflexes in patients with gastro-oesophageal reflux

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Abstract

Using five non-invasive tests, abnormalities of cardiovascular reflex function were found in 20 of 50 patients with gastro-oesophageal reflux. Abnormalities of pupil cycle time, an index of non-vagal parasympathetic function, were found in only a few patients, implying that the cardiovascular abnormalities observed were not part of a generalised parasympathetic defect. The findings are consistent with the hypothesis that an abnormality of vagal function may contribute to the pathogenesis of gastro-oesophageal reflux.

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Chakraborty, T. K., Ogilvie, A. L., Heading, R. C., & Ewing, D. J. (1989). Abnormal cardiovascular reflexes in patients with gastro-oesophageal reflux. Gut, 30(1), 46–49. https://doi.org/10.1136/gut.30.1.46

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