Ischemia/reperfusion injury (IRI) is a common cause of acute kidney injury (AKI) that is associated with a patient mortality of up to 50%. Currently there are not effective pharmacologic therapies for AKI. This Commentary highlights recent evidence indicating that 20-HETE plays an important role in IRI and that drugs that target this pathway have potential as therapeutic agents for AKI. © 2011 International Society of Nephrology.
CITATION STYLE
Roman, R. J., Akbulut, T., Park, F., & Regner, K. R. (2011). 20-HETE in acute kidney injury. Kidney International. Nature Publishing Group. https://doi.org/10.1038/ki.2010.396
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