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A novel tumour-based test to identify breast cancer due to BRCA1 and BRCA2 mutations

  • An Q
  • Jones L
  • Tapper W
  • et al.
Breast Cancer Research (2010) 12(S1)
DOI: 10.1186/bcr2528
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Abstract

Objective To develop a sensitive and specii c pathology-based predictor to improve identii cation of BRCA1 and BRCA2 gene carriers.Methods We assembled a training panel of breast cancer tumour blocks from 67 BRCA1, 71 BRCA2 associated and 105 sporadic young onset cases (

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An, Q., Jones, L., Tapper, W., Chelala, C., Iravani, M., MacKay, A., … Eccles, D. (2010). A novel tumour-based test to identify breast cancer due to BRCA1 and BRCA2 mutations. Breast Cancer Research, 12(S1). https://doi.org/10.1186/bcr2528

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