Phase-resolved doppler fourier domain optical coherence tomography in the in vivo mouse model

Abstract

Blood flow velocities within vasodynamic measurements in the in vivo mouse model were imaged by using phase-resolved Doppler Fourier Domain Optical Coherence Tomography with a spectrum read-out rate of 12 kHz. The high temporal resolution of the system is used to quantify the pulse from real-time cross-sectional images of the murine saphenous artery. The Doppler method was evaluated by imaging a 1% Intralipid emulsion flowing through a glass capillary with an inner diameter of approximately 320 μm. © 2009 Springer Berlin Heidelberg.