SVM-based local search for gene selection and classification of microarray data

Abstract

This paper presents a SVM-based local search (SVM-LS) approach to the problem of gene selection and classification of microarray data. The proposed approach is highlighted by the use of a SVM classifier both as an essential part of the evaluation function and as a "provider" of useful information for designing effective LS algorithms. The SVM-LS approach is assessed on a set of three well-known data sets and compared with some best algorithms from the literature. © Springer-Verlag Berlin Heidelberg 2008.