Alphavirus Structure

  • Harrison S
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Abstract

Alphavirus particles are roughly spherical, with three principal substructures---an outer glycoprotein shell, a lipid bilayer, and an RNA-containing core (nucleocapsid). The radial organization of these components is summarized in Fig. 1. The most extensive structural studies have been carried out on Sindbis virus and Semliki Forest virus (SFV). It is on these very similar viruses that the description below will focus.

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Harrison, S. C. (1986). Alphavirus Structure. In The Togaviridae and Flaviviridae (pp. 21–34). Springer New York. https://doi.org/10.1007/978-1-4757-0785-4_2

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