Lipid Goal attainment and prescription behavior in Asian patients with acute coronary syndromes: Experience from a tertiary hospital

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Abstract

Lipid goal attainment studies in Asian patients with acute coronary syndrome (ACS) are limited. The objectives of this study were to determine low-density lipoprotein cholesterol (LDL-C) goal attainment rate at 4 months, and to examine prescription behavior influencing lipid goal attainment in Asian patients with ACS. A retrospective analysis of 267 patients with ACS was performed. The mean follow-up duration was 41.2±10.7 months. LDL-C goal attainment rate was highest at 4 months (36.7%) but declined progressively throughout follow-up. More than 85% of patients were discharged with equipotent statin dose of 2 (equivalent to simvastatin 20 mg) or less. In patients who did not attain LDL-C goals, the statin dose remained low throughout follow-up because of a lack in responsive dose titration. Aggressive lipid-lowering therapy should be initiated early to improve goal attainment in these high-risk patients. © the author(s), publisher and licensee Libertas Academica Ltd.

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Chin, C. W., Gao, F., Le, T. T., & Tan, R. S. (2013). Lipid Goal attainment and prescription behavior in Asian patients with acute coronary syndromes: Experience from a tertiary hospital. Clinical Medicine Insights: Cardiology, 7, 51–57. https://doi.org/10.4137/CMC.S11488

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