Background: To determine whether items of the Chinese version of the Montreal Cognitive Assessment Basic (MoCA-BC) could discriminate among cognitively normal controls (NC), and those with mild cognitive impairment (MCI), mild Alzheimer's disease (AD), and moderate-severe (AD), as well as their sensitivity and specificity. Methods: MCI (n = 456), mild AD (n = 502) and moderate-severe AD (n = 102) patients were recruited from the memory clinic, Huashan Hospital, Shanghai, China. NC (n = 329) were recruited from health checkup outpatients. Five MoCA-BC item scores were collected in interviews. Results: The MoCA-BC orientation test had high sensitivity and specificity for discrimination among MCI, mild AD and moderate-severe AD. The delayed recall memory test had high sensitivity and specificity for MCI screening. The verbal fluency test was efficient for detecting MCI and differentiating AD severity. Conclusions: Various items of the MoCA-BC can identify MCI patients early and identify the severity of dementia.
CITATION STYLE
Zhang, Y. R., Ding, Y. L., Chen, K. L., Liu, Y., Wei, C., Zhai, T. T., … Dong, W. L. (2019). The items in the Chinese version of the Montreal cognitive assessment basic discriminate among different severities of Alzheimer’s disease. BMC Neurology, 19(1). https://doi.org/10.1186/s12883-019-1513-1
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